Detalhe da pesquisa
1.
Role of endopeptidases in peptidoglycan synthesis mediated by alternative cross-linking enzymes in Escherichia coli.
EMBO J
; 40(19): e108126, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34382698
2.
Monitoring Drug-Protein Interactions in the Bacterial Periplasm by Solution Nuclear Magnetic Resonance Spectroscopy.
J Am Chem Soc
; 146(13): 9252-9260, 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38500259
3.
Penicillin-Binding Proteins and Alternative Dual-Beta-Lactam Combinations for Serious Enterococcus faecalis Infections with Elevated Penicillin MICs.
Antimicrob Agents Chemother
; 67(2): e0087122, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36719223
4.
Partition of tRNAGly isoacceptors between protein and cell-wall peptidoglycan synthesis in Staphylococcus aureus.
Nucleic Acids Res
; 49(2): 684-699, 2021 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33367813
5.
Modulation of the Specificity of Carbapenems and Diazabicyclooctanes for Selective Activity against Mycobacterium tuberculosis.
Antimicrob Agents Chemother
; 66(9): e0235721, 2022 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35943263
6.
Synthesis of Carbapenems Containing Peptidoglycan Mimetics and Inhibition of the Cross-Linking Activity of a Transpeptidase of l,d Specificity.
Chemistry
; 27(10): 3542-3551, 2021 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33336443
7.
Click and Release Chemistry for Activity-Based Purification of ß-Lactam Targets.
Chemistry
; 27(28): 7687-7695, 2021 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33792096
8.
Copper inhibits peptidoglycan LD-transpeptidases suppressing ß-lactam resistance due to bypass of penicillin-binding proteins.
Proc Natl Acad Sci U S A
; 115(42): 10786-10791, 2018 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30275297
9.
Ceftazidime-Avibactam Resistance Mediated by the N346Y Substitution in Various AmpC ß-Lactamases.
Antimicrob Agents Chemother
; 64(6)2020 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32253219
10.
Inhibition Activity of Avibactam against Nocardia farcinica ß-Lactamase FARIFM10152.
Antimicrob Agents Chemother
; 64(2)2020 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31712200
11.
Impact of relebactam-mediated inhibition of Mycobacterium abscessus BlaMab ß-lactamase on the in vitro and intracellular efficacy of imipenem.
J Antimicrob Chemother
; 75(2): 379-383, 2020 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31637424
12.
In Vitro and Intracellular Activity of Imipenem Combined with Tedizolid, Rifabutin, and Avibactam against Mycobacterium abscessus.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30745387
13.
Negative Impact of Carbapenem Methylation on the Reactivity of ß-Lactams for Cysteine Acylation as Revealed by Quantum Calculations and Kinetic Analyses.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30718252
14.
Combination of Amino Acid Substitutions Leading to CTX-M-15-Mediated Resistance to the Ceftazidime-Avibactam Combination.
Antimicrob Agents Chemother
; 62(9)2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29941650
15.
In Vitro and Intracellular Activity of Imipenem Combined with Rifabutin and Avibactam against Mycobacterium abscessus.
Antimicrob Agents Chemother
; 62(8)2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29866869
16.
Peptidoglycan Cross-Linking Activity of l,d-Transpeptidases from Clostridium difficile and Inactivation of These Enzymes by ß-Lactams.
Antimicrob Agents Chemother
; 62(1)2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29061738
17.
Synthesis of Lipid-Carbohydrate-Peptidyl-RNA Conjugates to Explore the Limits Imposed by the Substrate Specificity of Cell Wall Enzymes on the Acquisition of Drug Resistance.
Chemistry
; 24(56): 14911-14915, 2018 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30020544
18.
Critical Impact of Peptidoglycan Precursor Amidation on the Activity of l,d-Transpeptidases from Enterococcus faecium and Mycobacterium tuberculosis.
Chemistry
; 24(22): 5743-5747, 2018 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29389045
19.
Synthesis of Avibactam Derivatives and Activity on ß-Lactamases and Peptidoglycan Biosynthesis Enzymes of Mycobacteria.
Chemistry
; 24(32): 8081-8086, 2018 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29601108
20.
Synthesis of tRNA analogues containing a terminal ribose locked in the South conformation to study tRNA-dependent enzymes.
Org Biomol Chem
; 16(11): 1903-1911, 2018 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29484333